Please note: This is a Single Viewer eCast registration for one participant for this eCast for both the live and on-demand version of this eCast. If you are interested in presenting this program to a group, please see the “eCast Registration Form– Group Viewing” form on the eCast program page.

Access instructions for the live eCast will be provided via email approximately 2-3 business days prior to the live program date. Access instructions for the on-demand version of this program will be provided via email approximately 7-10 business days after the live program has occurred and the on-demand version is available. If registering after the on-demand version is available, access is granted via the AABB Education Website at https://education.aabb.org.

Program Description: Hemorrhage remains a major cause of potentially preventable morbidity and mortality in patients. Massive blood loss is encountered in various clinical situations such as trauma, major surgery, gastrointestinal bleeds, and obstetrical hemorrhage. Massive transfusion protocols (MTPs) are activated by clinicians in response to massive bleeding. MTPs have a predefined ratio of red blood cells, plasma, and platelet units in each pack for transfusion. These protocols ensure rapid and timely delivery of blood products to facilitate resuscitation. Along with conventional blood products, other blood products and pharmaceutical agents can also be of benefit. Drugs such as tranexamic acid have been shown to significantly reduce mortality in trauma patients and have been found to be beneficial in reducing bleeding in cardiac surgeries. There has also been a shift in greater use of whole blood as it has been shown that blood component therapy does not contain the same levels of platelets, coagulation factors and fibrinogen found in whole blood. This eCast will further explore the use of these and other non-conventional blood products in the setting of massive transfusion. This program will be presented though the lens of the laboratory personnel (blood banker) vs the clinician (trauma surgeon).