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Pathogen Inactivation: The Penultimate Paradigm Shift

Pathogen Inactivation: The Penultimate Paradigm Shift

Product Code: 102118

In this imperfect world, pathogen inactivation has been sought as a way to achieve a zero-risk blood supply.

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Back to Pathogen Inactivation: The Penultimate Paradigm Shift

In this imperfect world, pathogen inactivation has been sought as a way to achieve a zero-risk blood supply. Although no group of techniques can be relied upon as a true panacea, pathogen inactivation is a bold leap in a positive direction. With the assumption of remarkably low risk, albeit at a higher cost, these techniques hold promise for addressing not only the known safety concerns, including bacterial contamination, but also the “next new virus” for which we are unprepared. This comprehensive and timely volume presents the basic concepts, reviews the research performed to date, and provides practical implementation advice from an international panel of “early adopters.”

Topics addressed:

  • The rationale for pathogen inactivation.
  • The challenges posed by some targets of inactivation.
  • Assessing the toxic effects.
  • Methods and considerations for red cells, platelets, and plasma.
  • Practical experience from several European sites.
  • Regulations and implementation from both North American and European perspectives.

This text will be of interest to those who are already using pathogen inactivation techniques (to compare and refine their operations), practitioners who are considering pathogen inactivation for their facilities in the near future (to identify aspects for consideration), and those who just want to be more knowledgeable about it (to be ready when asked to “step up”).

View Table of Contents (pdf)

View Preface (pdf)

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